Scalp Neuropathy in Androgenetic Alopecia
Trichodynia is defined as a painful sensation in the skin of the scalp or the hair without an underlying cutaneous disease. The term “trichodynia” (cutaneous dysesthesia syndrome) has also been proposed for discomfort, pain, burning, or stinging of the scalp related to diffuse alopecia. Probably, the diffuse alopecia or telogen effluvium and trichodynia are related. The underlying mechanisms creating the pain are not clear, though it has been proposed that it is probably multi-etiological. The most accepted hypotheses are increased expression of the neuropeptide substance P, underlying psychiatric disorders, nutritional deficiencies, and perifollicular inflammation. Although dealing with trichodynia can be distressing and literature support is weak, there are a number of treatments available. Complaints such as pain and burning of the scalp in patients with diffuse alopecia were described in the earlier dermatology literature. Both such studies and clinical observations have led to the idea that the diffuse alopecia or telogen effluvium (TE) and trichodynia are related. By definition, TE is a nonscarring and diffuses hair loss from the scalp that occurs a few months after a triggering event.
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